Arash Omidi; Fatemeh Namazi; Hamidreza Pourmirzaei; Mahdi Mohebbi-Fani
Abstract
Squamous cell carcinoma (SCC) is a tumor consisting of squamous epithelial cells. This tumor is relatively uncommon in goats. In this report, we discuss clinical, gross and histopathological features of SCC in six goats. The goats were referred to the veterinary clinic with a progressive ulcerative and ...
Read More
Squamous cell carcinoma (SCC) is a tumor consisting of squamous epithelial cells. This tumor is relatively uncommon in goats. In this report, we discuss clinical, gross and histopathological features of SCC in six goats. The goats were referred to the veterinary clinic with a progressive ulcerative and hemorrhagic mass located in the perineal area. The vital signs (temperature, pulse rate, respiration rate) were normal. Biopsy specimens were taken and histopathological examinations were done. The tumor cells were large and had an abundant eosinophilic cytoplasm, ovoid nuclei with a prominent nucleolus. Keratin tonofibers and keratin pearls were also seen. The mitotic figures were moderate. The mass was found to be a moderately differentiated SCC. Ulceration with infiltration of neutrophils was observed on the surface of the tumors. The SCC tumors are uncommon in goats and have multi-factorial etiology. Age, ultraviolet (UV) light exposure, lack of epidermis pigmentation, and viruses may be involved in the presence of SCC.
Arash Omidi; Mohammad Fathi; Mahsa Asiaban
Abstract
Background: The knowledge of blood parameters is important for assessing the physiological status and health of animals. OBJECTIVES: This study was conducted to determine the effect of heavy pregnancy on some serum indices of dromedary camels. METHODS: Twenty clinically healthy female dromedary camels ...
Read More
Background: The knowledge of blood parameters is important for assessing the physiological status and health of animals. OBJECTIVES: This study was conducted to determine the effect of heavy pregnancy on some serum indices of dromedary camels. METHODS: Twenty clinically healthy female dromedary camels aged between 4-5 years were divided into two equal groups: I: pregnant camels in their last trimester; and II: non-pregnant age-matched controls. The concentration of glucose, calcium, phosphorus, albumin, total protein, uric acid, blood urea nitrogen (BUN), creatinine and the activity of aspartate amino transferase (AST), alanine amino transferase (ALT), and gamma glutamyl transferase (GGT), was measured. RESULTS: The results of this study show that the concentrations of glucose, calcium and phosphorus remained unchanged in pregnant camels compared to non-pregnant ones. The concentrations of serum BUN and creatinine in pregnant camels were higher, and these aforementioned differences were significant (p=0. 02 and 0.003 respectively). GGT activity was lower in pregnant than in non-pregnant camels (p=0. 04). CONCLUSIONS: The increase in BUN and creatinine levels might be part of the homeorhetic mechanisms for adaptation of camels during heavy pregnancy. The high urea-recycling rate in camels may transfer urea to the gastrointestinal tract as a source of “non-protein nitrogen” instead of being excreted as urine. The reduction of GGT as at the time of heavy pregnancy, may be attributed to its conversion to glutathione, as an antioxidant.
Arash Omidi; Fateme Izadi Yazanabadi; Ukabod Esmaeilpour; Mohammad-ali Behdani; Mohammad Reza Aslani
Abstract
Background: Some species of grass cause poisoning and hepatogenous photosensitization in animals. OBJECTIVES: Feeding trials were conducted in sheep and goats to evaluate the hepatotoxic effects of Setaria italica (S. italica). METHODS: Twelve indigenous male sheep and goats were used in this study. ...
Read More
Background: Some species of grass cause poisoning and hepatogenous photosensitization in animals. OBJECTIVES: Feeding trials were conducted in sheep and goats to evaluate the hepatotoxic effects of Setaria italica (S. italica). METHODS: Twelve indigenous male sheep and goats were used in this study. The animals were kept outdoors against prevailing climatic conditions. They were fed with S. italica freely for 50 days. Some biochemical factors associated with liver function, such as total bilirubin (TBIL), direct bilirubin (BC), aspartate amino transferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyltransferase (GGT) activities, blood urea nitrogen (BUN), total protein (TP), and albumin (ALB), were measured on day 0, 7, 14, 21, 28, 35, 42, and 49 of the experiment. On the 50th day, the animals were sacrificed and necropsied, then the gall bladder and livers were removed for pathological study. Blood samples on day 0 (prior to feeding with S. italica) were set as the control group. RESULTS: Three sheep and 3 goats showed signs of intoxication, including facial edema, mucus hyperemia, runny nose, lacrimation, and icterus. Post-mortem examination revealed varying degrees of generalized icterus, degeneration, necrosis and cell swelling of hepatocytes, formation of acidophilic bodies, and mild hyperplasia in biliary ducts. CONCLUSIONS: Clinical signs, laboratory findings, and necropsy findings, support the potential of S. italica in the induction of hepatotoxicity and secondary photosensitivity in sheep and goats.
Arash Omidi; Zhila Sajedi; Mohammad Montazer Torbati; Mohsen Mostafai
Abstract
BACKGROUND: The knowledge in blood constituents isimportant for assessing the physiological status and the health ofanimals. Only a limited number of two-humped camels (Camelusbactrianus) were reared in Ardabil province, northwest of Iran.OBJECTIVES:The present study was carried out to find out whetherthe ...
Read More
BACKGROUND: The knowledge in blood constituents isimportant for assessing the physiological status and the health ofanimals. Only a limited number of two-humped camels (Camelusbactrianus) were reared in Ardabil province, northwest of Iran.OBJECTIVES:The present study was carried out to find out whetherthe sex and pregnancy affect thyroid hormones, lipid andlipoprotein profile, and selected biochemical factors in healthyIranian Bactrian camels. METHODS:The evaluated herd containedtwenty clinical healthy Bactrian camels, aged between four andthirteen years. Six of them were non-pregnant, five in the late periodof pregnancy, and nine were male camels. Blood samples (10 mL)were collected from the jugular vein of camels in spring 2013 duringtwo consecutive days. All samples were centrifuged at 3000× rpmfor 15 min and sera were refrigerated at -21°C until analysis.Thyroid function tests were carried out by measuring serum levelsof thyroid stimulating hormone (TSH), free and total thyroxin(fT4), (T4), and free and total triiodothyronine (fT3), (T3) bycommercially available radio immunoassay kits. The biochemicalparameters were measured using a standard autoanalyser(Hitachi717, Boehringer. Mannheim, Germany). RESULTS: Thelevels of fT4, HDL-Cholesterol, ALP, and glucose in the sera ofpregnant camels were significantly lower than the male and nonpregnantcamels. The serum levels of other parameters were notsignificantly different among the groups. CONCLUSIONS: Thepresent study revealed that heavy pregnancy has a profound effecton certain serum biochemical parameters in Bactrian camels.