TY - JOUR ID - 21357 TI - Effects of Fig tree (Ficus carica) leaf extracts on serum and liver cholesterol levels in hyperlipidemic rats JO - Iranian Journal of Veterinary Medicine JA - IJVM LA - en SN - 2251-8894 AU - رسولی, علی AU - Fatemi ardestani, Ahmad AU - Asadi, Farzad AU - Salehi, Mohammad AD - Y1 - 2010 PY - 2010 VL - 4 IS - 2 SP - EP - DO - 10.22059/ijvm.2010.21357 N2 - The effects of three Ficus carica leaf extracts on the total cholesterol levels (TC) of serum and liver were investigated in experimentally-induced nutritional hyperlipidemic rats. In nine treatment groups (n=5 each group), hyperlipidemic rats were treated daily with hydromethanolic (total) extract (2.5, 5, 10 mg/kg, intraperitoneal [ip]) and its aqueous fractions, namely fraction A (10, 50, 250 mg/kg, ip) and fraction B (10, 50, 250 mg/kg, ip) for eight days. In negative and positive control groups, animals received normal and hyperlipidemic diets with ip injections of normal saline, respectively. The lipid-lowering effect of total extract on liver cholesterol was more pronounced than that of serum. Fraction A caused a significant dose-dependent decrease in cholesterol levels in both the serum and the liver (p UR - https://ijvm.ut.ac.ir/article_21357.html L1 - https://ijvm.ut.ac.ir/article_21357_c34a6a8e4183db925fab72271c56e0a9.pdf ER -