University of Tehran Iranian Journal of Veterinary Medicine 2251-8894 7 4 2014 01 01 The effects of fasting on some biochemical factors of liver, serum and clinical signs in cattle آثار پرهیز غذایی بر برخی فاکتورهای بیوشیمیایی خون، کبد و نشانه‌های بالینی در گاو 277 285 36288 10.22059/ijvm.2013.36288 EN Sareh Rezaei Graduated from The Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Mohamad Rahim Haji Hajilolaei Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Ali Shahriary Department of Basic Sciences, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Alireza Ghadiri Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Mohammad Nouri Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Journal Article 2013 08 05 BACKGROUND: Fasting is an alternative method to induce<br />anorexia. OBJECTIVES: The biochemical factors of liver and<br />serum and clinical signs were measured and documented in five<br />non-lactating, non-pregnant cows following eight days of fasting.<br />METHODS:Five crossbred, non-lactating, and non-pregnant<br />cattle were used in this study. They were fasted for 8 days_ total<br />food deprivation; however, they had free access to water. Liver<br />biopsies were carried out one day before food deprivation (day<br />0) and 8 days after food deprivation by ultrasound-guided<br />biopsy. Blood samples were taken from the jugular vein before<br />and during fasting. The concentrations of triglyceride (TG), total<br />lipids, glycogen, phospholipids, and total protein in liver and<br />NEFA, BHBA, TG, total cholesterol, glucose, total lipid, APO<br />A1, and APO B in blood serum were measured and compared.<br />RESULTS: The results of this study showed that fasting for 8 days<br />reduces respiratory rate by 52% and heart rate by 12.5% and has<br />no significant effect on rectal temperature. The concentrations of<br />the liver triglyceride (TG) and glycogen significantly increased<br />(p=0.046) and decreased (p=0.007) on day 8, respectively. There<br />were no significant differences in the content of liver<br />phospholipids (p=0.83), total lipids (p=0.29), and total protein<br />(p=0.23). The serum concentrations of NEFA and BHBA<br />increased significantly (p=0.008) at the end of fasting period. No<br />significant differences in the concentrations of serum TG<br />(p=0.057), total cholesterol (p=0.93), glucose (p=0.108), total<br />lipid (p=0.27), APO A1 (p=0.762), and APO B (p=0.92) were<br />noticed on days 0 and 8. CONCLUSIONS: The results of the<br />present study showed that fasting, like anorexia (as a result of<br />diseases), induces fat mobilization from adipose tissue in<br />response to the induced negative energy balance. https://ijvm.ut.ac.ir/article_36288_e359378a0c6cfe01758e31c9fdc9ae0f.pdf