University of Tehran Iranian Journal of Veterinary Medicine 2251-8894 16 3 2022 08 01 Feasibility of Using Evidence-Based Virtopsy to Answer the Possible Clinical and Post-Mortem Questions, in Veterinary Practice امکان سنجی استفاده از ویرتوپسی مبتنی بر شواهد برای پاسخ به سؤالات احتمالی بالینی و پس از مرگ، در دامپزشکی 311 336 84961 10.22059/ijvm.2021.331329.1005197 EN Mohammad Molazem Arezoo Ramezani Undergraduate student of veterinary medicine, faculty of veterinary medicine, university of Tehran Sarang Soroori Department of surgery and radiology, Faculty of veterinary medicine, university of Tehran, Tehran, Iran Zahra Jafary Giv Department of surgery and radiology, Faculty of veterinary medicine, university of Tehran, Tehran, Iran Sara Shokrpoor Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Urs Geissbuehler Department of Clinical Veterinary Medicine, Division of Clinical Radiology, Vetsuisse Faculty of Bern, University of Bern, Bern, Switzerland Journal Article 2022 01 03 Postmortem examination is an important part in evidence-based medicine to understand deterioration of clinical signs or causes of death in euthanized or deceased individual animals or even populations. <br />The object of postmortem analysis is to improve clinical treatment and therapy, to confirm suspected diagnosis, to manage breeding strategies or to clarify in forensic cases the conditions, which had led to death (neglect, animal abuse). In analogy to virtopsy in human medicine, Diagnostic imaging modalities have been applied in post mortem veterinary medicine, which we call Vetvirtopsy.<br />We hypothesize, that Vetvirtopsy can be used as a method for certain clinical/post mortem questions to improve the reliability of the diagnosis. In some questions, Vetvirtopsy actually can replace conventional necropsy. The aim of this overview study is to compare Vetvirtopsy to conventional necropsy in variable causes of death in animals and to define its possibilities and limitations. <br />Deceased or euthanized pets and wild animals were collected. The methods used are imaging techniques such as postmortem digital radiography, postmortem ultrasound, postmortem computed tomography and postmortem magnetic resonance tomography in combination with image-guided tissue sampling to address the open questions about clinical symptoms or causes of their death. <br />The case series in this project shown that using diagnostic imaging technique is feasible in answering different clinical ante-mortem and post-mortem clinical and forensic questions; however, there is an interdisciplinary collaboration between the diagnostic imaging and sampling under imaging guidance. https://ijvm.ut.ac.ir/article_84961_ebf0d36226a5592d80ad257bf1f56013.pdf