This report describes the histological and immunohistochemical features of a small intestinal tumor that resembled a human gastrointestinal stromal tumor (GISTs) in a seven-year-old male cross-breed dog. This was unique because of the expression of desmin by the tumor. Grossly, the white-gray tumor measured 8.0 × 4.0 × 6.5 cm and was 760 gram in weight. It was cystic and enveloped the jejunum. Histopathologically, long spindle-shaped cells were arranged densely in the interwoven pattern. The tumor cells had a low rate of mitosis, were pleomorphic, and were positive for vimentin, ?-smooth muscle actin, desmin, S100 and C-KIT and negative for CD34 on immunohistochemistry. The expression of desmin in the cytoplasm of this tumor cells is a rare event in these types of tumors.
Hesaraki,S , Nasiri,S M and Seraji,A R . (2010). Desmin expression by a gastrointestinal stromal tumor in a dog. (e22099). Iranian Journal of Veterinary Medicine, 4(4), e22099 doi: 10.22059/ijvm.2010.22099
MLA
Hesaraki,S , , Nasiri,S M , and Seraji,A R . "Desmin expression by a gastrointestinal stromal tumor in a dog" .e22099 , Iranian Journal of Veterinary Medicine, 4, 4, 2010, e22099. doi: 10.22059/ijvm.2010.22099
HARVARD
Hesaraki S, Nasiri S M, Seraji A R. (2010). 'Desmin expression by a gastrointestinal stromal tumor in a dog', Iranian Journal of Veterinary Medicine, 4(4), e22099. doi: 10.22059/ijvm.2010.22099
CHICAGO
S Hesaraki, S M Nasiri and A R Seraji, "Desmin expression by a gastrointestinal stromal tumor in a dog," Iranian Journal of Veterinary Medicine, 4 4 (2010): e22099, doi: 10.22059/ijvm.2010.22099
VANCOUVER
Hesaraki S, Nasiri S M, Seraji A R. Desmin expression by a gastrointestinal stromal tumor in a dog. Iran J Vet Med. 2010;4(4):e22099. doi: 10.22059/ijvm.2010.22099
