This report describes the histological and immunohistochemical features of a small intestinal tumor that resembled a human gastrointestinal stromal tumor (GISTs) in a seven-year-old male cross-breed dog. This was unique because of the expression of desmin by the tumor. Grossly, the white-gray tumor measured 8.0 × 4.0 × 6.5 cm and was 760 gram in weight. It was cystic and enveloped the jejunum. Histopathologically, long spindle-shaped cells were arranged densely in the interwoven pattern. The tumor cells had a low rate of mitosis, were pleomorphic, and were positive for vimentin, ?-smooth muscle actin, desmin, S100 and C-KIT and negative for CD34 on immunohistochemistry. The expression of desmin in the cytoplasm of this tumor cells is a rare event in these types of tumors.
Hesaraki, S. , Nasiri, S. M. and Seraji, A. R. (2010). Desmin expression by a gastrointestinal stromal tumor in a dog. Iranian Journal of Veterinary Medicine, 4(4), -. doi: 10.22059/ijvm.2010.22099
MLA
Hesaraki, S. , , Nasiri, S. M. , and Seraji, A. R. . "Desmin expression by a gastrointestinal stromal tumor in a dog", Iranian Journal of Veterinary Medicine, 4, 4, 2010, -. doi: 10.22059/ijvm.2010.22099
HARVARD
Hesaraki, S., Nasiri, S. M., Seraji, A. R. (2010). 'Desmin expression by a gastrointestinal stromal tumor in a dog', Iranian Journal of Veterinary Medicine, 4(4), pp. -. doi: 10.22059/ijvm.2010.22099
CHICAGO
S. Hesaraki , S. M. Nasiri and A. R. Seraji, "Desmin expression by a gastrointestinal stromal tumor in a dog," Iranian Journal of Veterinary Medicine, 4 4 (2010): -, doi: 10.22059/ijvm.2010.22099
VANCOUVER
Hesaraki, S., Nasiri, S. M., Seraji, A. R. Desmin expression by a gastrointestinal stromal tumor in a dog. Iranian Journal of Veterinary Medicine, 2010; 4(4): -. doi: 10.22059/ijvm.2010.22099
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