Iranian Journal of Veterinary Medicine

Iranian Journal of Veterinary Medicine

Antiparasitic efficacy of worm wood (Artemisia absinthium) alcoholic extract on syphacia obvolata

Authors
محمد رضا یوسفی 1
Mohadeseh Abuhosseini Tabari 2
Goodarz Sadeghi Hashjin 2
Mohammad Kazem Kouhi 3
1 گروه انگل شناسی، دانشگاه آزاد اسلامی واحد بابل
2 گروه فارماکولوژی، دانشکده دامپزشکی دانشگاه تهران
3 گروه علوم پایه، دانشکده دامپزشکی دانشگاه تهران
10.22059/ijvm.2012.24625
Abstract
BACKGROUNDS: Occurrence of resistance against antiparasitic drugs has made it essential for researchers to find new sources for antiparasitic drugs. OBJECTIVES: This study was performed to determine the efficiency of alcoholic extract of worm wood (Artemisia absinthium) on Syphasia parasite. METHODS: Artemisia absinthium extract was examined on 3 groups of mice at 2.5%, 5% and 10% concentrations. A group of positive control received pyrantel pamoate, while negative control group was treated by a solution containing no extract. Mice were treated orally 28 days after infection by Syphacia eggs. The efficacy of treatment was determined by Syphacia eggs in the feces. RESULTS: In groups that received either 5% or 10% concentrations of A. absinthium extract or pyrantel pamoate, microscopic examinations of the feces demonstrated no Syphacia eggs. CONCLUSIONS: Data obtained from the present study showed that the alcoholic extract of Artemisia absinthium may lead to a decline in the number of Syphacia eggs in the feces with minimal side effects. The extract of this plant can probably be used as a suitable alternative in the treatment of some parasitic diseases.
Iranian Journal of Veterinary Medicine
Volume 6, Issue 1 - Serial Number 848859
14 Iranian Journal Of Veterinary Medicine
March and April 2012
Pages 47-50