Iranian Journal of Veterinary Medicine

Iranian Journal of Veterinary Medicine

Mixed cutaneous round cells tumor in a cock (Gallus domesticus): A case report

Authors
سید مصطفی پیغمبری 1
Jamshid Razmyar 2
Seyed Mostafa Peighambari 3
Zolfaghar Rajabi 4
Mohammad Reza Sadeghi 5
Isa Jahanzad 6
1 گروه پاتوبیولوژی، دانشکده دامپزشکی دانشگاه لرستان
2 گروه علوم درمانگاهی، دانشکده دامپزشکی دانشگاه فردوسی مشهد
3 گروه علوم درمانگاهی، دانشکده دامپزشکی دانشگاه تهران
4 گروه علوم درمانگاهی، دانشکده دامپزشکی دانشگاه تبریز
5 گروه میکروبیولوژی، دانشکده پیرا دامپزشکی دانشگاه بوعلی سینا همدان
6 گروه پاتولوژی، دانشکده پزشکی دانشگاه علوم پزشکی تهران
10.22059/ijvm.2012.28957
Abstract
Cutaneous round cell tumors have been classified as mast cell tumor (MCT), histiocytoma (HCT), lymphosarcoma, undif-ferentiated round cell tumors and occasionally rhabdomyosarcoma in veterinary medicine. An adult cock (Gallus domesticus) showing a large solitary integument mass raised on dorso bilateral of cervical part, extending to intercapsular and cranial mid part of the back was referred to the birds clinic of the faculty of veterinary medicine at the university of Tehran. Microscopic examination revealed she-eted cells with large, round to oval nuclei with each one containing one or more prominent nucleoli with scant cytoplasm. The myofibrils of the neck were degenerated by aggressive tumor cells. The condition was differentiated from other round cell tumors by electron microscope, histochemical staining, as well as the application of a large panel of antibodies. Polymerase chain re-action failed to confirm the involvement of both Marek's disease virus and avian leukosis virus subgroup-J. It was concluded that the tumor cells were consistent with both B-cell lymphocytes and histiocytes that unusually covered the entire dermal layer of dorsal neck skin. This unusual cutaneous lymphoma was named as lymphoblastic histiocytoma.
Iranian Journal of Veterinary Medicine
Volume 6, Issue 2 - Serial Number 1177763
15 Iranian Journal Of Veterinary Medicine
May and June 2012
Pages 123-128