Raoofi, A., Yourdkhani, S., Bokaie, S. (2017). Comparison of serum triiodothyronine, tetraiodothyronine and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township. Iranian Journal of Veterinary Medicine, 11(3), 243-248. doi: 10.22059/ijvm.2017.215631.1004764
Afshin Raoofi; Soroush Yourdkhani; Saied Bokaie. "Comparison of serum triiodothyronine, tetraiodothyronine and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township". Iranian Journal of Veterinary Medicine, 11, 3, 2017, 243-248. doi: 10.22059/ijvm.2017.215631.1004764
Raoofi, A., Yourdkhani, S., Bokaie, S. (2017). 'Comparison of serum triiodothyronine, tetraiodothyronine and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township', Iranian Journal of Veterinary Medicine, 11(3), pp. 243-248. doi: 10.22059/ijvm.2017.215631.1004764
Raoofi, A., Yourdkhani, S., Bokaie, S. Comparison of serum triiodothyronine, tetraiodothyronine and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township. Iranian Journal of Veterinary Medicine, 2017; 11(3): 243-248. doi: 10.22059/ijvm.2017.215631.1004764
Comparison of serum triiodothyronine, tetraiodothyronine and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township
1Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran
2Department of Clinical Sciences , Faculty of Veterinary Medicine, Garmsar Branch , Islamic Azad University
3Division of Epidemiology and Zoonoses, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran
Abstract
BACKGROUND: The preliminary survey made about congenital goiter in goats in Garmsar township indicated that the disease occurs much more in Beetal-cross than native goats raised in the same area. OBJECTIVES: The aim of the present study was to compare of serum triiodothyronine (T3), tetraiodothyronine (T4) and thyroid stimulating hormone concentrations in pregnant and lactating Beetal-cross and native goats in Garmsar township. METHODS: One hundred Beetal-cross (n=50) and native (n=50) does in 4 groups (25 pregnant Beetal-cross, 25 lactating Beetal-cross, 25 pregnant native and 25 lactating native) were used in this study. Blood samples were obtained via jugular venipuncture and analyzed for serum T3, T4 and TSH concentrations. RESULTS: Breed had a significant (P<0.05) effect on T4 concentration and pregnancy had a significant (P<0.05) effect on T3 and TSH concentrations. No significant differences were seen for serum T3, T4 and TSH concentrations between pregnant and lactating native does. However, in the pregnant Beetal-cross, serum T3 and T4 concentrations were lower (P<0.05) and TSH concentration was higher (P<0.05) than lactating Beetal-cross does. CONCLUSIONS: The results of the present study highlight the relationships between thyroid activity and breed in the goat species that may play a role in more occurrence of congenital goiter in Beetal-cross in Garmsar township.
مقایسه غلظت سرمی هورمونهای تری یدوتیرونین، تترایدوتیرونین و هورمون محرک تیروئید در بزهای آبستن و شیروار از دو نژاد دورگ بیتال و بومی در شهرستان گرمسار
Authors [Persian]
افشین رئوفی1; سروش یوردخانی2; سعید بکایی3
1گروه بیماریهای داخلی، دانشکده دامپزشکی دانشگاه تهران
2گروه علوم درمانگاهی، دانشکده دامپزشکی واحد گرمسار، دانشگاه آزاد اسلامی
3بخش اپیدمیولوژی و بیماریهای مشترک، گروه بهداشت مواد غذایی و کنترل کیفی، دانشکده دامپزشکی دانشگاه
Abstract [Persian]
زمینه مطالعه: بر اساس بررسیهای قبلی در شهرستان گرمسار موارد وقوع گواتر مادرزادی در بزهای نژاد دورگ بیتال بسیار بیشتر از بزهای بومی منطقه می باشد. هدف: این تحقیق با هدف مقایسه غلظت سرمی تری یدوتیرونین (T3)، تترا یدوتیرونین (T4) و هورمون محرک تیروئید(TSH) در بزهای آبستن و شیروار از دو نژاد دورگ بیتال و بومی در شهرستان گرمسار انجام شد. روش کار: از تعداد 100 راس بز شامل 50 راس نژاد دورگ بیتال و 50 راس نژاد بومی منطقه گرمسار در 4 گروه 25تایی (دورگ بیتال آبستن، دورگ بیتال شیروار، بومی آبستن و بومی شیروار) خونگیری از ورید وداج صورت گرفت و غلظت سرمی T3، T4 وTSH اندازه گیری شد. نتایج: نتایج این تحقیق نشان داد که نژاد تاثیر معنی داری (0.05>p) بر میزان T4 سرم و آبستنی تاثیر معنی داری (0.05>p) بر میزان T3 و TSH سرم داشته است. در بزهای بومی تفاوت معنی داری از نظر میزان T3، T4 وTSH بین دامهای آبستن و شیروار دیده نشد ولی در بزهای آبستن دورگ بیتال به طور معنی داری (0.05>p) غلظت سرمی T3 و T4 کمتر و غلظت سرمی TSH بیشتر از دامهای شیروار بود. نتیجه گیری نهایی: نتایج این بررسی حاکی از آن است که می تواند ارتباطی بین فعالیت غده تیروئید و نژاد در بز وجود داشته باشد و این موضوع ممکن است نقشی در وقوع بیشتر گواتر مادرزادی در بزهای نژاد دورگ بیتال در شهرستان گرمسار ایفا نماید.
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