The Role of Fabricated Coral Shell Hydroxyapatite Powder in the Healing of Large Size Mandibular Bone Gap Defect in Dogs

Document Type : Original Articles

Authors

1 Department of Surgery and Obstetric , College of Veterinary Medicine, University of Tikrit , Tikrit , Iraq

2 Department of Surgery and Theriogenology, College of Veterinary Medicine, University of Mosul, Mosul, Iraq.

10.22059/ijvm.2023.361777.1005417

Abstract

BAGROUND : The reconstruction of mandibular bone defect comprised a real challenge and difficult task for surgeons, biomaterial bone substitutes are the most used material for reconstruction mandibular bone defect.
OBJECTIVES: This study explored the role of fabricated Hydroxyapatite (HAp) powder from the coral shell in healing critical size mandibles gap in dogs.
METHODS: HAp was prepared by hydrothermal method from Coral shells. Characterization of the fabricated coral shell was done by X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), and Energy dispersive X-ray spectroscopy(EDX). The designed research was performed on eighteen dogs of both sexes weighted and aged (20 ± 0.5 kg), (2±0.6 years). The experiment was divided into two equal groups. Animals underwent experimental defects at the ventral surface of the lower mandible about (14, 5 mm).
RESULTS:The results of (XRD) represented high crystallinity, the (EDX) results indicated the surface morphology of distributed particles of calcium, phosphor, carbon, and oxygen, respectively, and the FESEM results suggested that the surface morphology of (HAp) appears as a spherical particle that regularly distributed within the sample. In the (HAp)group, at 30 days, the FESEM images show that the defective gap completely closed, and the center of the defect was filled with a thick layer of osteoid matrix. Radiographically in (HAp) group at 30 days post-surgery indicated a well-defined circular radiolucent bone gap at the caudal portion of the mandible, with a partially sclerosed margin. Macroscopically at 30 days, the gap appears very small in size, invaded with new bone formation.
CONCLUSION: In conclusion, the recycling (HAp) from coral shells has practical value in the reconstitution of the mandibular gap and the radiological and critical properties of prepared (HAp) emphasize this outcome.

Keywords


Article Title [Persian]

نقش پودر هیدروکسی آپاتیت پوسته مرجانی ساخته شده در بهبود نقص استخوان فک پایین در اندازه بزرگ در سگ ها

Authors [Persian]

  • علی قاضی عطیه 1
  • لیت محمود الکتان 2
1 گروه جراحی و مامایی، دانشکده دامپزشکی، دانشگاه تکریت، تکریت، عراق
2 گروه جراحی و مامایی، دانشکده دامپزشکی، دانشگاه موصل، موصل، عراق.

Keywords [Persian]

  • شکاف استخوان
  • ترمیم استخوان
  • پوسته مرجانی
  • سایز بزرگ
  • فک پایین