Background: The broiler chicken population is currently facing a pressing issue in the form of bacterial infections, which significantly impact their growth and developmental processes. Glycyrrhizin (GL), a compound discovered in licorice, has been found to enhance growth performance in broiler chickens by improving feed efficiency and organ development. It also has immunomodulatory and anti-inflammatory properties, which contribute to overall poultry health. Objectives: GL may modulate appetite and serum markers by mitigating inflammation in chickens. Methods: The study investigated the effects of GL and LPS on broilers. 24 one-day-old male Arian broiler chickens were divided into 4 groups: a control group and 3 treatment groups receiving lipopolysaccharide (LPS) alone or with GL at 2 different dosages. Treatments were administered intravenously on day 20, and feed intake and blood samples were monitored. Results: LPS injection significantly reduced feed intake compared to the control group at 4.5, 5, and 6 h. after injection (P< 0.05). Furthermore, the co-administration of LPS+GL resulted in a dose-dependent increase in cumulative feed consumption compared to the LPS group at 4.5, 5, and 6 h. following the injection. Additionally, the groups treated with LPS and GL showed reduced activity of AST and ALT enzymes relative to the group that received only LPS, suggesting that GL may exert a hepatoprotective effect. GL was found to mitigate the negative effects of LPS and improve the A/G ratio, highlighting its potential as an anti-inflammatory agent. Conclusion: GL positively influences appetite and liver function in inflamed Arian broilers
Nowrouzpour, M. , Rahdari, A. and Hamidi, F. (2024). Effects of intravenous injection of glycyrrhizin on serum biochemical parameters and appetite in inflamed Arian broiler chickens. Iranian Journal of Veterinary Medicine, (), -. doi: 10.22059/ijvm.2024.378110.1005600
MLA
Nowrouzpour, M. , , Rahdari, A. , and Hamidi, F. . "Effects of intravenous injection of glycyrrhizin on serum biochemical parameters and appetite in inflamed Arian broiler chickens", Iranian Journal of Veterinary Medicine, , , 2024, -. doi: 10.22059/ijvm.2024.378110.1005600
HARVARD
Nowrouzpour, M., Rahdari, A., Hamidi, F. (2024). 'Effects of intravenous injection of glycyrrhizin on serum biochemical parameters and appetite in inflamed Arian broiler chickens', Iranian Journal of Veterinary Medicine, (), pp. -. doi: 10.22059/ijvm.2024.378110.1005600
CHICAGO
M. Nowrouzpour , A. Rahdari and F. Hamidi, "Effects of intravenous injection of glycyrrhizin on serum biochemical parameters and appetite in inflamed Arian broiler chickens," Iranian Journal of Veterinary Medicine, (2024): -, doi: 10.22059/ijvm.2024.378110.1005600
VANCOUVER
Nowrouzpour, M., Rahdari, A., Hamidi, F. Effects of intravenous injection of glycyrrhizin on serum biochemical parameters and appetite in inflamed Arian broiler chickens. Iranian Journal of Veterinary Medicine, 2024; (): -. doi: 10.22059/ijvm.2024.378110.1005600